Skip to Main Content

I am pleased to present the 8th edition of Neonatology. The first edition was published in 1988 and was started during my neonatology fellowship at University of Kentucky Medical Center in Lexington. The origins of the manual were fairly simple and started as a series of handouts designed to help students and residents make it through their neonatal intensive care unit rotation. Because of a complicated twin pregnancy during my fellowship, I had to delay my training and complete my required neonatology fellowship time at Johns Hopkins University.

While the roots of this manual can be traced back to the University of Kentucky during my fellowship with Dr. Doug Cunningham, it was ultimately completed while I was a fellow at Johns Hopkins University and working at the newly established Bayview campus in Baltimore under Dr. Fabien Eyal. This has made the book somewhat unique because it was originally written from the perspective of a trainee in 2 different neonatology programs. This simple fact, along with the addition of other authors from around the United States and the world, has brought together a diverse group of contributors. I hope you will agree that this approach provides a comprehensive overview of the field of neonatology.

Dr. Doug Cunningham has worked as associate editor on this manual since its inception 7 editions ago. For this, our 8th edition, he has passed the baton to Dr. Fayez Bany-Mohammed from the University of California, Irvine School of Medicine. Dr. Mohammed has been involved with the manual since the 5th edition and has established himself as one of our most outstanding authors. He has previously contributed multiple chapters with a concise writing style that made him a perfect fit to fill Dr. Cunningham's shoes. I also want to publicly express my thanks to Dr. Cunningham. If it was not for his mentorship, this manual would not be in existence. He gave me special permission to develop the earliest versions of the manual during my dedicated fellowship research time. In a most fitting tribute to his contributions to the field of neonatology and his major longstanding contributions to this manual, we have dedicated this edition to Dr. Doug Cunningham.

In this 8th edition, the table of contents was reformatted to make it more user friendly and hopefully more logical. Section I includes essential prenatal and postnatal topics such as "Fetal Assessment," "Obstetric Anesthesia and the Neonate," "Resuscitation of the Newborn," and "Neonatal Transport." Section II encompasses basic assessment and management of a newborn with a new chapter addressing "The Golden Hour." Section III includes advanced management topics such as the evolving areas of complementary and integrative therapies and 2 new chapters: "Genetic and Genomic Testing in the Newborn Period" and "Neonatal Palliative Care." Section IV includes all the basic and advanced bedside procedures commonly used in neonatology. We have added an entire new section on point-of-care ultrasound in Chapter 44. We have also included point-of-care ultrasound information on pertinent procedures. One of the most popular sections of the book, the "On-Call Problems" section, now includes a total of 35 common neonatal problems with 1 new problem added: "Abdominal Distension." Section VI, "Diseases and Disorders," covers all the common and a few not so common, but clinically important, diseases of the neonate. We have added a new subsection on "Infectious Diseases" to encompass the growing literature on infectious diseases that may be present in a neonate. Two new chapters were added in this section addressing dengue infection and Zika virus. The section on neonatal pharmacology includes significant updates of medications commonly used in neonates. Since there are relatively few medications formally approved for use in neonates, the medication information has been carefully curated by our outstanding group of neonatal PharmDs. We believe it to be the most comprehensive list of medications found in a manual such as ours. The "Effects of Drugs and Substances on Lactation and Infants" chapter has been revised to include the most common medications that might be used by a breast-feeding mother. The appendices include other useful reference tables and information. A hallmark of our book has been noting areas that are "controversial," and this edition continues that tradition.

Another exciting and evolving aspect of this manual is its global reach. As our readership has grown worldwide, we have added to our international editorial board. These board members are from many countries: Poland, Jordan, United Arab Emirates, Costa Rica, Saudi Arabia, Peru, French Polynesia, the Netherlands, the Philippines, Finland, India, Israel, Bahamas, Canada, and Australia. These physicians, along with our many international contributors, help to make the manual a useful reference worldwide. The manual has been previously translated into 12 different languages over the past 25 years. These translations include Russian, Spanish, Portuguese, Polish, Chinese (short and long form), Turkish, Greek, Yugoslavian (now Serbian), Italian, Hungarian, and Korean.

I would like to personally thank Dr. Fabien Eyal, my senior associate editor and my fellowship mentor at Johns Hopkins, and Dr. Fayez Bany-Mohammed, my associate editor, for assigning, composing, and reviewing many sections of the manual and for their willingness to always be available for questions. I also want to thank my section editors. Dr. Brooke Vergales, the procedure section editor, spearheaded the procedure chapter updates. I had 3 wonderful PharmDs—Pui-Man (Julia) Ho, Kristin Bohannon, and Valerie Nolt—who worked tirelessly to update the pharmacology and breast-feeding sections, along with their new medication tables, which will enhance several chapters. In addition to their long-term commitment to this manual, the associate editors have brought together outstanding authors from all over the United States and the international community.

I also express appreciation to Louise Bierig, Andrew Moyer, and the editorial and production staff at McGraw-Hill and their colleagues abroad (especially Tania Andrabi) for their extensive assistance during the 2-year journey to complete this new edition. A special thanks to my loving husband Lenny, who helped me extensively concerning matters of editorial content, and my awesome children Patrick, Andrew, Leonard, and Michael (the PALM team), who helped troubleshoot computer issues and tolerated many sacrifices while I worked on this and many previous editions of the book over the past 30 years. I owe a debt of gratitude to all of my mother's caregivers (Edie Brewer, Lynn Finney, Skylar Finney, Meryle Voytilla, Calia Broaddus, Anick Biatchon, Veronica Messina, Lillian Colon, and Maria Romero) who took excellent care of my wonderful elderly mother, Nancy Murray Lacy, so I could have the time to work on this edition and to Maisie, our emotional support Bearded Collie, who provided me with humor and love.

Please visit our website,, for additional information on this manual and for links to enhanced online content for supplemental images, indicated by the symbol [image] that appears in several chapters. References for each chapter can be accessed from

Your suggestions and comments about this manual are always welcome. Readers' comments have helped shape the content of our manual over the previous 7 editions.

Tricia Lacy Gomella, MD

Pop-up div Successfully Displayed

This div only appears when the trigger link is hovered over. Otherwise it is hidden from view.