Skip to Main Content

We have a new app!

Take the Access library with you wherever you go—easy access to books, videos, images, podcasts, personalized features, and more.

Download the Access App here: iOS and Android. Learn more here!

INTRODUCTION

Neonatal hepatitis is an inflammation of the liver tissue in a newborn infant and may be caused by many infectious and noninfectious agents. Typically, viral hepatitis refers to several clinically similar diseases that differ in cause and epidemiology. These include hepatitis A, B, C, D (delta), and E. Chronic lifelong infection has only been documented with hepatitis B and hepatitis C viruses.

The differential diagnosis of newborn liver disease includes idiopathic neonatal hepatitis (giant cell), biliary atresia, metabolic disorders, antitrypsin deficiency, cystic fibrosis, iron storage disease, and other infectious agents that cause hepatocellular injury (eg, cytomegalovirus [CMV], herpes simplex, rubella, varicella, toxoplasmosis, Listeria monocytogenes, syphilis, and tuberculosis, as well as bacterial sepsis, which can cause nonspecific hepatic dysfunction). Table 136–1 outlines various hepatitis panel tests useful in the management of this disease. Isolation precautions for all infectious diseases, including maternal and neonatal precautions, breast feeding, and visiting issues, can be found in Appendix F. This chapter will go over neonatal hepatitis caused by Hepatitis A, B, C, D, and E.

Table 136–1.HEPATITIS TESTING

Pop-up div Successfully Displayed

This div only appears when the trigger link is hovered over. Otherwise it is hidden from view.