Hereditary (Isolated Cataracts) | Smith-Magenis syndrome (17p11-) | Metaphyseal and epiphyseal dysplasia, unusual
facies and cataracts |
Anterior polar | 18p- |
Lamellar, zonular, nuclear cataracts | Turner syndrome | Syndrome of hypohidrotic ectodermal dysplasia
and cataracts |
Bilateral posterior lenticonus | Cataracts Associated with Systemic Disease |
Discoloration of anterior capsule (eg, green) | Galactosemia (transferase deficiency) | Familial organic aciduria with cardiomyopathy |
Cataracts, microcornea, and microphthalmia | Hallermann-Streiff syndrome | Mevalonic aciduria |
Cataracts, microcornea, and dental anomalies
(Nance-Horan syndrome) | Rhizomelic chondrodysplasia punctata | Walker-Warburg syndrome |
Lowe syndrome (oculocerebrorenal) | Neonatal adrenoleukodystrophy |
Sutural opacities (including carrier of Nance-Horan trait) | Marinesco-Sjögren syndrome (MR, hypotonia,
dwarfism, ataxia, and cataracts) | Martsolf syndrome (MR, dwarfism, hypogonadism) |
Carrier of chondrodysplasia punctata | CAMFAK syndrome (microcephaly and cataracts) |
Ectopia lentis et pupillae | MICRO syndrome (mental retardation, microcephaly,
microphthalmia, and cataracts) | Ellis van Creveld syndrome (chondroectodermal
dysplasia) |
Pulverulent cataract |
Lowe syndrome carrier | Kniest syndrome (skeletal dysplasia) | Wide fontanels and sutures and sutural opacities |
Aculeiform cataract | Incontinentia pigmenti | Soto syndrome (cerebral gigantism) |
Congenital central pouchlike cataract | Atopic dermatitis | CHARGE syndrome |
Hyperferritinemia cataract | Smith-Lemli-Opitz syndrome | Cohen-Holmes-Mirhosseini-Walton syndrome |
Idiopathic | Infantile hypoglycemia | DeBarsy syndrome |
Unilateral/bilateral cortical cataracts | Congenital cataracts associated with skeletal
and cardiac myopathy | Roberts pseudothalidomide syndrome |
Unilateral posterior lenticonus | Cerebro-ocular myopathy syndrome |
Isolated lens capsule pigmentation | Mitochondrial complex I deficiency | Osteoporosis and pseudoglioma syndrome |
Residual anterior capsule pupillary membrane plaque | Pearson syndrome (mitochondrial) | Spondylo-ocular syndrome |
Embryopathic | Rubinstein-Taybi syndrome | Papillorenal syndrome |
Maternal rubella syndrome | Blepharophimosis with somatofacial dysmorphism
(Schwartz-Aberfeld) | Cataracts Associated with Primary Ocular Anomalies |
Severe toxoplasmosis |
Herpes simplex infection | Congenital cataract, renal necrosis, and encephalopathy | Persistent hyperplastic primary vitreous (PHPV,
persistent fetal circulation) |
Maternal varicella |
Cytomegalovirus | Phenylketonuria | Aniridia |
Trauma | Hereditary spherocytosis | Peters anomaly |
Birth | Trichomegaly, spherocytosis, and bilateral cataracts | Ectopia lentis et pupillae |
Nonaccidental trauma (child abuse) | Oxycephaly | Retinochoroidal coloboma |
Cataracts of Prematurity | Schafer syndrome (mental retardation, dwarfism,
hyperkeratosis, nail abnormality) | Congenital retinal nonattachment |
Transient cataracts | Microphthalmia and cataracts with or without
other ocular defects |
Cataracts following laser photocoagulation therapy | Siemens syndrome (cataracts and skin hypoplasia) |
Chromosomal Disorders (not a complete list) | Oculocerebral syndrome with aminoaciduria
and keratosis follicularis | Bhaduri syndrome: cataracts, blepharophimosis,
and iris hypoplasia |
Cri Du Chat (5p-) |
Aniridia in WAGR syndrome (11p13-) | Maple syrup urine disease | Familial iridocorneal goniodysgenesis |
13q- | Cataracts, microcephaly, kyphosis, and limited
joint movement | |
Trisomy 13, 18, or 21 | |