Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content +++ Cutaneous Manifestations of HIV Infection (Chronic Varicella Zoster Infection) ++ Figure 18-1 Cutaneous manifestations of HIV infection (chronic varicella zoster infection) Figure 18-1 illustrates a form of infection with varicella zoster virus that is unique to patients with immune suppression from HIV. The 6-year-old child pictured here developed recurrent vesicular and ulcerative lesions of the trunk and extremities following an episode of chickenpox. The lesions contain numerous multinucleated giant cells and are culture-positive for varicella zoster virus. Graphic Jump LocationView Full Size||Download Slide (.ppt) +++ Cutaneous Manifestations of HIV Infection (Herpes Zoster Infection) ++ Figure 18-2 Cutaneous manifestations of HIV infection (herpes zoster infection) In addition to chronic infections with varicella zoster, many patients develop unusual forms of herpes zoster infection. These patients also develop prolonged episodes of shingles that do not respond quickly to appropriate antiviral agents; they may also develop generalized varicella zoster infections. Graphic Jump LocationView Full Size||Download Slide (.ppt) +++ Cutaneous Manifestations of HIV Infection (Scarring from Herpes Zoster) ++ Figure 18-3 Cutaneous manifestations of HIV infection (scarring from herpes zoster) Figure 18-3 shows a 3-year-old girl developed herpes zoster as an early manifestation of her immune deficiency. Despite therapy with intravenous acyclovir, severe scarring resulted. Herpes zoster generally occurs more frequently in children who have had chickenpox very early in life. Although herpes zoster is certainly seen in the healthy child, its occurrence in a child who is at risk for HIV infection should signal concern. Graphic Jump LocationView Full Size||Download Slide (.ppt) +++ Cutaneous Manifestations of HIV Infection (Candidal Paronychias and Nail Dystrophy) ++ Figure 18-4 Cutaneous manifestations of HIV infection (candidal paronychias and nail dystrophy) Candidiasis is the most common mucocutaneous manifestation of pediatric HIV infection. Children with AIDS or lesser forms of HIV-related disease frequently develop oral thrush, which recurs or persists despite topical antifungal therapy. Recalcitrant infections of the diaper area and neck folds are also common. Illustrated in Fig. 18-4 are chronic paronychias with a resultant nail dystrophy. Graphic Jump LocationView Full Size||Download Slide (.ppt) +++ Cutaneous Manifestations of Hiv Infection (Drug Eruption) ++ Figure 18-5 Cutaneous manifestations of HIV infection (drug eruption) Drug eruptions, usually due to therapy with trimethoprim-sulfamethoxazole, are particularly common among children with HIV infection. This child shown in Fig. 18-5 developed Steven-Johnson syndrome, which is a fairly frequent occurrence among children infected with HIV. The frequency of drug eruptions in children with AIDS illustrates the complex effect of HIV on the immune system. Graphic Jump LocationView Full Size||Download Slide (.ppt) +++ Cutaneous Manifestations of HIV Infection (Molluscum Contagiosum) ++ Figure 18-6 Cutaneous manifestations of HIV infection (molluscum contagiosum) Children in general are prone to infection with the virus causing molluscum contagiosum. Children infected with ... Your Access profile is currently affiliated with '[InstitutionA]' and is in the process of switching affiliations to '[InstitutionB]'. Please click ‘Continue’ to continue the affiliation switch, otherwise click ‘Cancel’ to cancel signing in. Get Free Access Through Your Institution Learn how to see if your library subscribes to McGraw Hill Medical products. Subscribe: Institutional or Individual Sign In Username Error: Please enter User Name Password Error: Please enter Password Forgot Password? Forgot Username? Sign in via OpenAthens Sign in via Shibboleth You already have access! Please proceed to your institution's subscription. Create a free a profile for additional features.