TY - CHAP M1 - Book, Section TI - Cardiogenic Shock A1 - Bronicki, Ronald A. A1 - Price, Jack A2 - Kline, Mark W. PY - 2018 T2 - Rudolph's Pediatrics, 23e AB - The clinical syndrome of shock has great potential for significant morbidity and mortality and is one of the most challenging conditions to treat. In accordance with Barcroft’s original construct for conceptualizing shock that was published nearly 100 years ago, shock results from 1 or more of the following mechanisms: impaired oxygenation or hypoxic hypoxia, reduced oxygen carrying capacity or anemic hypoxia, limited cardiac output or stagnant hypoxia, or impaired oxygen utilization or histotoxic hypoxia (eg, cyanide toxicity). Shock results from inadequate oxygen delivery relative to oxygen demand, and if the body’s intrinsic compensatory mechanisms of increased cardiac output and oxygen extraction are insufficient, or left inadequately treated, this can rapidly result in organ dysfunction or failure. The etiologies of shock are broad, as are its manifestations, and in this review we will discuss the pathophysiology, assessment, and treatment of cardiogenic shock. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1182926062 ER -