TY - CHAP M1 - Book, Section TI - Leukemia, Acute Myeloid (AML) A1 - Hay, Jr, William W. A1 - Levin, Myron J. A1 - Deterding, Robin R. A1 - Abzug, Mark J. PY - 2017 T2 - Quick Medical Diagnosis & Treatment Pediatrics AB - Approximately 500 new cases occur per year in children and adolescents in the United StatesAlthough AML accounts for only 25% of all leukemias in this age group, it is responsible for at least one-third of deaths from leukemia in children and teenagersCongenital conditions associated with an increased risk of AML includeDiamond-Blackfan anemiaNeurofibromatosisDown syndromeWiskott-Aldrich, KostmannLi-Fraumeni syndromesChromosomal instability syndromes such as Fanconi anemiaAcquired risk factors include exposure to ionizing radiation, cytotoxic chemotherapeutic agents, and benzenesHowever, the vast majority of patients have no identifiable risk factors SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1145456769 ER -