TY - CHAP M1 - Book, Section TI - Pulmonary Hypoplasia A1 - Hay, Jr, William W. A1 - Levin, Myron J. A1 - Deterding, Robin R. A1 - Abzug, Mark J. PY - 2017 T2 - Quick Medical Diagnosis & Treatment Pediatrics AB - Defined as incomplete development of one or both lungsCharacterized by a reduction in alveolar number and a reduction in airway branchesPresent in up to 10–15% of perinatal autopsiesCongenital diaphragmatic hernia is the most common cause, with an incidence of 1:2200 birthsCan be a result ofAn intrathoracic mass, resulting in lack of space for the lungs to growDecreased size of the thoraxDecreased fetal breathing movementsDecreased blood flow to the lungsPrimary mesodermal defect affecting multiple organ systemsOther causes includeExtralobar sequestrationDiaphragmatic eventration or hypoplasiaThoracic neuroblastomaFetal hydropsFetal hydrochylothoraxChest cage abnormalities, diaphragmatic elevation, oligohydramnios, chromosomal abnormalities, severe musculoskeletal disorders, and cardiac lesions may also result in hypoplastic lungs SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1145458196 ER -