TY - CHAP M1 - Book, Section TI - Trisomy 18 Syndrome A1 - Hay, Jr, William W. A1 - Levin, Myron J. A1 - Deterding, Robin R. A1 - Abzug, Mark J. PY - 2017 T2 - Quick Medical Diagnosis & Treatment Pediatrics AB - Incidence is about 1:4000 live birthsRatio of affected males to females is approximately 1:3Characterized byPrenatal and postnatal growth retardation, which is often severeHypertonicityComplications are related to associated anomaliesDeath is often caused by heart failure or pneumonia and usually occurs in infancy or early childhoodSmall percentage reach adulthood; usually show significant cognitive disabilitiesA support group for families is called SOFT (see http://www.trisomy.org/) SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/13 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1145459239 ER -