TY - CHAP M1 - Book, Section TI - Fetal Cardiology A1 - Falkensammer, Christine B. A1 - Hornberger, Lisa K. A2 - Kline, Mark W. PY - 2018 T2 - Rudolph's Pediatrics, 23e AB - The origins of fetal cardiology were in the novel and still relevant fetal lamb investigations of Rudolph and Heymann. From these early studies, we began to understand normal fetal cardiovascular physiology and developed hypotheses regarding the evolution of congenital heart disease (CHD) in utero and its influence on fetal circulation. With advances in ultrasound technology in the late 1970s and 1980s, it became possible to demonstrate normal fetal cardiac anatomy and document growth of the cardiac chambers and great arteries. Doppler investigations in the 1980s and 1990s added insight into developmental changes in normal human fetal circulation and cardiovascular function. Initial reports describing prenatal detection of fetal CHD documented a more severe spectrum of disease than that encountered after birth. This was at least in part a consequence of the ease with which the more severe pathology, including fetal hydrops, was recognized at routine ultrasound assessment. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1182913418 ER -