TY - CHAP M1 - Book, Section TI - Increased Susceptibility to Infections A1 - Chinen, Javier A2 - Kline, Mark W. PY - 2018 T2 - Rudolph's Pediatrics, 23e AB - Many children are evaluated by their physicians because of recurrent infections, a relatively common complaint in early childhood. These children are considered to have an increased susceptibility to infections as compared with children of similar age. Both extrinsic and host factors can increase the risk of developing infections, and may be found in most such cases (Table 183-1). Identification and management of these underlying conditions would result in a reduction in frequency of infectons. Examples of extrinsic factors include human immunodeficiency virus infection, use of immunosuppressor drugs, high exposure to infectious agents in a daycare setting, presence of foreign bodies, or exposure to parental smoking. Host factors that increase risks of developing infections include genetic deficiencies of the immune response and several other conditions: respiratory allergies, abnormal anatomy, and diseases affecting barriers or epithelia such as cystic fibrosis. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1182931536 ER -