TY - CHAP M1 - Book, Section TI - Skin Disease in Immunosuppressed Hosts A1 - Berger, Emily M. A1 - Perman, Marissa J. A2 - Zaoutis, Lisa B. A2 - Chiang, Vincent W. PY - 2017 T2 - Comprehensive Pediatric Hospital Medicine, 2e AB - A wide variety of cutaneous disorders may affect immunocompromised pediatric patients. Children can be immunocompromised due to an underlying malignancy, immunodeficiency, or secondary to immunosuppressive therapy. Chronic immunosuppressive therapies may be administered for numerous reasons including solid organ transplantation and chronic conditions. In addition, immunosuppression may result from chemotherapeutic treatment regimens for malignancies or conditioning regimens in preparation for bone marrow or stem cell transplantation. The cutaneous disorders associated with immunosuppression range in severity. Even the most banal skin lesions in immunocompromised children can herald life-threatening conditions. Skin biopsies can thus be useful tools in immunosuppressed patients with skin lesions to aid in diagnosis.1 Skin lesions are most frequently a consequence of drug side effects or infection caused by immunosuppression.2,3 Skin disorders affecting immunocompromised patients may occur acutely during high levels of immunosuppression (such as in transplant patients during the early post-transplant period or during periods of acute rejection), while other skin eruptions may be secondary to exposure to various medications. Table 66-1 displays a range of cutaneous lesions seen in immunocompromised patients. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/11/09 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1146115986 ER -