TY - CHAP M1 - Book, Section TI - Disorders of Calcium Metabolism A1 - Kenigsberg, Lisa A1 - Agarwal, Chhavi A2 - Zaoutis, Lisa B. A2 - Chiang, Vincent W. PY - 2017 T2 - Comprehensive Pediatric Hospital Medicine, 2e AB - Calcium is the most abundant mineral in the body and is required for proper functioning of numerous intracellular and extracellular processes, including muscle contraction, nerve conduction, hormone release, and blood coagulation. Calcium also plays a unique role in intracellular signaling and is involved in the regulation of enzyme activity. Maintenance of calcium homeostasis is therefore critical. Ionized calcium, which is responsible for the physiologic effects, is maintained under normal conditions within a narrow normal range of approximately 4.5 to 5.3 ng/dL (1.12–1.32 mmol/L), with higher levels in neonates and infants. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/20 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1146116429 ER -