TY - CHAP M1 - Book, Section TI - Juvenile Scleroderma A1 - Zulian, Francesco A2 - Kline, Mark W. PY - 2018 T2 - Rudolph's Pediatrics, 23e AB - Juvenile scleroderma syndromes are multisystem autoimmune rheumatic diseases for which the unifying characteristic is the development of hard skin before age 16. They can be separated into 2 main categories: 1) juvenile systemic sclerosis (JSSc), characterized by diffuse skin sclerosis involving many sites of the body together with internal organ involvement, and 2) juvenile localized scleroderma (JLS), characterized by circumscribed skin induration but no vascular or internal organ involvement. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1182932530 ER -