TY - CHAP M1 - Book, Section TI - Malignant Liver Tumors A1 - Tomlinson, Gail E. A1 - Katzenstein, Howard M. A2 - Kline, Mark W. PY - 2018 T2 - Rudolph's Pediatrics, 23e AB - Liver tumors represent approximately 1% of all childhood cancers. There are approximately 100 to 150 new cases of liver cancer diagnosed in children each year in the United States. Hepatoblastoma, the most common malignant tumor of the liver, accounts for two-thirds of all liver cancer in children. Hepatoblastoma typically occurs in the very young child, with a mean age of onset between 18 to 20 months and 95% of cases occurring before 5 years of age. The incidence of hepatoblastoma has approximately doubled over the past few decades. Hepatoblastoma is considered an embryonal tumor because, histologically, tumor cells resemble cells seen in the developing liver. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1182911529 ER -