TY - CHAP M1 - Book, Section TI - Disorders of Metabolism of Lysine and Related Compounds A1 - Koeller, David M. A2 - Kline, Mark W. PY - 2018 T2 - Rudolph's Pediatrics, 23e AB - Lysine is an essential amino acid that can be degraded via 2 alternative pathways. The predominant route is via the saccharopine pathway, with the peroxisomal pipecolic acid pathway playing a relatively minor role. Degradation of lysine through either pathway leads to the formation of α-aminoadipic semialdehyde, which is catabolized to acetyl-coenzyme A (CoA) and enters the tricarboxylic acid (TCA) cycle. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1182928542 ER -