TY - CHAP M1 - Book, Section TI - Immunizations A1 - Meissner, H. Cody A2 - Kline, Mark W. PY - 2018 T2 - Rudolph's Pediatrics, 23e AB - Childhood immunizations represent one of the great public health achievements of the 20th and 21st centuries. According to the World Health Organization, immunization prevented at least 2 million child deaths in 2003 alone. Less than 250 years after Edward Jenner reported that inoculation with cowpox protected against smallpox, immunization against 15 different diseases before age 2 is routinely recommended in the United States. The individual, societal, and economic benefits of disease prevention resulting from the childhood and adult immunization programs in the United States are without question. A report from the Centers for Disease Control and Prevention (CDC) describing the benefits of vaccination of the 2009 birth cohort through 18 years of age estimated that 20 million cases of vaccine-preventable disease will not occur, 42,000 early deaths related to these diseases will be avoided, and $76 billion in direct and indirect costs will be averted. This economic benefit stands in stark contrast to the comparatively small cost for vaccine purchases. The estimated vaccine purchasing cost for a similar birth cohort based on 2015 pricing is $7.8 billion based on CDC cost and $11.6 billion at private sector pricing. The benefit from the reduction in suffering because of vaccine-preventable disease avoidance cannot be quantified. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1182934960 ER -