TY - CHAP M1 - Book, Section TI - Motor Disorders of the Stomach, Small Bowel, and Colon A1 - Altaf, Muhammad A. A1 - Sood, Manu R. A2 - Kline, Mark W. PY - 2018 T2 - Rudolph's Pediatrics, 23e AB - Propulsion of the gastrointestinal (GI) luminal contents requires coordinated contractions of the intestinal smooth muscle in response to input from the enteric neurons. The enteric nervous system is capable of independent function, which is modulated by motor input from the brain through the sympathetic and parasympathetic branches of the autonomic nervous system. GI motor function develops between 26 and 36 weeks of intrauterine life, but it is not fully developed until 36 weeks’ gestation. Thus, it is not unusual for preterm infants to have poor gastric emptying (GE) and feeding intolerance. GI motility disorders result from weak or uncoordinated contractions due to abnormalities of the neuromuscular apparatus or abnormal sensory and motor input from the brain. These disorders range in severity from mild, recurrent abdominal pain to severe chronic intestinal pseudo-obstruction syndrome (CIP) with intestinal failure. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1182908102 ER -