TY - CHAP M1 - Book, Section TI - Retinopathy of Prematurity A1 - Bhatt, Amit A1 - Coats, David K. A2 - Kline, Mark W. PY - 2018 T2 - Rudolph's Pediatrics, 23e AB - Retinopathy of prematurity (ROP) is a disorder that affects the developing retinal blood vessels of premature infants. It is the leading cause of both acquired and preventable childhood blindness in the United States. The disease was first recognized in the 1940s and was initially thought to be due to the normal primitive vascular system in the vitreous cavity persisting in an abnormal fibrotic state. By 1952, ROP became recognized as an acquired disease, and in 1955, the role of excessive supplementary oxygen for premature infants was proven to be a significant causative factor. Despite many improvements in neonatal care practices, ROP continues into the 21st century as a major complication of premature birth. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1182927028 ER -