TY - CHAP M1 - Book, Section TI - Shock A1 - Rozenfeld, Ranna A. PY - 2018 T2 - The PICU Handbook AB - Shock is a state of circulatory dysfunction that results in insufficient oxygen delivery and other substrate to meet tissue metabolic demands.1 Inadequate oxygen delivery leads to a shift to anaerobic metabolism, eventually resulting in lactate production and metabolic acidosis.2 If this state persists, it can lead to multiple organ dysfunction and death. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1152487887 ER -