TY - CHAP M1 - Book, Section TI - Congenital Infections A1 - Barrett, Renee E. A1 - Gallagher, Patrick G. A2 - Shah, Samir S. A2 - Kemper, Alex R. A2 - Ratner, Adam J. PY - 2019 T2 - Pediatric Infectious Diseases: Essentials for Practice, 2e AB - Congenital infections, historically referred to as TORCH infections, comprise a group of diseases that affect the fetus and newborn. Classically, the acronym TORCH represented toxoplasmosis, other (traditionally syphilis), rubella, cytomegalovirus (CMV), and herpes simplex virus (HSV). The “other” category has expanded to include human immunodeficiency virus (HIV), enterovirus, parvovirus, varicella, and most recently, Zika virus. These congenital infections share many clinical manifestations. Consequently, the differential diagnosis of one congenital infection includes the others (Table 53-1). The prevalence of various congenital infections is variable. Infection due to rubella and toxoplasmosis is rarely seen in the United States, while CMV is common, representing a significant public health concern. Although HIV can be a congenital infection, it is more commonly acquired perinatally. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/18 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1157323102 ER -