TY - CHAP M1 - Book, Section TI - Darier-White Disease A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Engelhardt, Thomas PY - 2019 T2 - Syndromes: Rapid Recognition and Perioperative Implications, 2e AB - A slowly progressive disorder involving the skin and causing severe keratinization. The lesions usually coalesce and result in crusted papillomatous lesions, sometimes accompanied with pus. The papules are also known as keratotic papules, keratosis follicularis, or dyskeratosis follicularis. Milder forms are more common and usually consist of skin rashes that flare up under certain conditions such as high humidity, stress or wearing tight-fitting clothes. The diagnostic is often established with the presence of poorly formed fingernails containing longitudinal white and red striations. This feature is pathognomonic. The onset may be as early as teenage years, but typically is observed during the third decade. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1164067497 ER -