TY - CHAP M1 - Book, Section TI - Friedreich Ataxia (FRDA) A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Engelhardt, Thomas PY - 2019 T2 - Syndromes: Rapid Recognition and Perioperative Implications, 2e AB - It is a genetic disorder characterized by the presence of progressive dysfunction of the posterior spinal cord, cerebellum (ataxia, nystagmus), and peripheral nerves. It typically becomes apparent before adolescence. Clinical features include unsteady posture, frequent falling, progressive ataxia, characteristic foot deformities, increasing incoordination of the arms and hands, dysarthria, and nystagmus. It may be associated with cardiomyopathy, chest pain, arrhythmias, and diabetes mellitus. All patients have normal intelligence. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1164070327 ER -