TY - CHAP M1 - Book, Section TI - Milton Disease A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Engelhardt, Thomas PY - 2019 T2 - Syndromes: Rapid Recognition and Perioperative Implications, 2e AB - It is a disorder of complement regulation in which C1 esterase inhibitor (C1INH), an inhibitor of spontaneous activation of C1, is lacking. This produces circumscribed, nonpitting subepithelial edema involving the lips, eyelids, tongue, larynx, pharynx, respiratory tract, gastrointestinal tract, renal system, and occasionally the central nervous system. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1164078870 ER -