TY - CHAP M1 - Book, Section TI - Pearson Syndrome A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Engelhardt, Thomas PY - 2019 T2 - Syndromes: Rapid Recognition and Perioperative Implications, 2e AB - Mitochondrial Cytopathy Disease presenting in infancy as refractive sideroblastic anemia, pancytopenia, defective oxidative phosphorylation, exocrine pancreatic insufficiency, and variable hepatic, renal, and endocrine failure. Death often occurs in infancy as a consequence of infection or metabolic crisis. Those who survive the first year of life present with ☞Kearns-Sayre Syndrome (progressive mitochondrial disorder with progressive external ophthalmoplegia and weakness of skeletal muscle). SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1164081146 ER -