TY - CHAP M1 - Book, Section TI - Cyanosis A1 - Gomella, Tricia Lacy A1 - Eyal, Fabien G. A1 - Bany-Mohammed, Fayez PY - 2020 T2 - Gomella's Neonatology: Management, Procedures, On-Call Problems, Diseases, and Drugs, 8e AB - During a physical examination, an infant appears blue. Cyanosis is a physical sign indicating a bluish/purplish discoloration of the skin and/or mucous membranes. There are many different types of cyanosis, and it is important to differentiate physiologic versus pathologic cyanosis. This chapter will focus mainly on central cyanosis because it is a potentially serious condition that requires an immediate evaluation. The differential diagnosis of central cyanosis includes disorders involving an increase in deoxygenated hemoglobin (respiratory, cardiovascular, neurologic, or other) or hematologic disorders involving abnormal hemoglobin (methemoglobinemia/sulfhemoglobinemia). Early diagnosis and treatment for any cyanotic infant is essential. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/16 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1168356709 ER -