TY - CHAP M1 - Book, Section TI - Eye Discharge and Conjunctivitis A1 - Gomella, Tricia Lacy A1 - Eyal, Fabien G. A1 - Bany-Mohammed, Fayez PY - 2020 T2 - Gomella's Neonatology: Management, Procedures, On-Call Problems, Diseases, and Drugs, 8e AB - A purulent eye discharge is noted in a 3-day-old infant. Eye discharge in a neonate is usually caused by neonatal conjunctivitis (also known as ophthalmia neonatorum) or congenital nasolacrimal duct obstruction (CNLDO or congenital dacryostenosis). Neonatal conjunctivitis (conjunctivitis occurring within the first 4 weeks of life) is an inflammation of the surface or covering of the eye that presents with eye discharge and hyperemia. It is the most common ocular disease in neonates. Etiology is chemical, bacterial, or viral. Most infections are acquired during vaginal delivery, but ascending infection can occur. In the United States, the incidence of infectious conjunctivitis is 1% to 2%, and in the world, it is 0.9% to 21%. Neonates with conjunctivitis require a thorough clinical and appropriate laboratory evaluation so appropriate treatment can be started as soon as possible if necessary. CNLDO is a membranous obstruction at the valve of Hasner, which is at the distal end of the nasolacrimal duct. Incidence is 6% to 20% in infants (studies show higher incidence in preterm infants when compared to full-term infants). The symptoms are persistent tearing and a mucoid discharge in the inner corner of the eye. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1168356743 ER -