TY - CHAP M1 - Book, Section TI - Pneumothorax A1 - Gomella, Tricia Lacy A1 - Eyal, Fabien G. A1 - Bany-Mohammed, Fayez PY - 2020 T2 - Gomella's Neonatology: Management, Procedures, On-Call Problems, Diseases, and Drugs, 8e AB - An infant with respiratory distress may have a pneumothorax. A pneumothorax is the abnormal accumulation of air in the pleural space, between the visceral and parietal pleura. It can develop spontaneously (idiopathic or from underlying lung disease) or be secondary to trauma. Pathophysiology involves an increased intra-alveolar pressure, which causes alveolar rupture and results in interstitial air; this air then dissects along the perivascular spaces and ruptures into the pleural space. A pneumothorax occurs more commonly in the neonatal period than any other time in life. Incidence is approximately 1% to 2% in term newborns and approximately 6% in premature infants. A pneumothorax is generally characterized as spontaneous, traumatic, tension, or persistent. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/16 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1168356988 ER -