TY - CHAP M1 - Book, Section TI - Malformations of Cortical Development: Proliferation Disorders A1 - Malinger, Gustavo A1 - Birnbaum, Roee A1 - Krajden Haratz, Karina A2 - Malinger, Gustavo A2 - Monteagudo, Ana A2 - Pilu, Gianluigi A2 - Paladini, Dario A2 - Timor-Tritsch, Ilan E. PY - 2023 T2 - Timor's Ultrasonography of the Prenatal Brain, 4e AB - Key PointsNeuronal proliferation, migration and organization start relatively late in pregnancy and do not end until after delivery.In the absence of associated malformations, microcephaly and macrocephaly are rarely diagnosed before birth or even in the newborn.The majority of fetuses with a head circumference between -2 and -3SD will develop normally.When a suspicion is raised genetic and pediatric neurology consultations are indicated. In low-risk patients, these signs may represent the only possibility for prenatal diagnosis.Exomic sequencing if available must be considered if chromosomal microarray is normal or inconclusive. SN - PB - McGraw Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1194696098 ER -