TY - CHAP M1 - Book, Section TI - Chapter 65. Reproductive Growth and Development in the Male Adolescent A1 - Breland, David J. A1 - Rubinstein, Mark L. A2 - Rudolph, Colin D. A2 - Rudolph, Abraham M. A2 - Lister, George E. A2 - First, Lewis R. A2 - Gershon, Anne A. PY - 2011 T2 - Rudolph's Pediatrics, 22e AB - Testicular growth and maturation are largely influenced by testosterone, which is produced by the testicle both before and after birth.1 Testosterone production is regulated centrally by the hypothalamic-pituitary-testicular axis as well as intragonadally. Testosterone effects include embryologic male genital differentiation, neonatal imprinting of androgen-dependent target tissue, maturation of the genitalia at puberty, growth of skeletal muscle, deepening of the voice from laryngeal growth, epiphyseal cartilage growth during puberty, male hair growth and distribution, erythropoiesis, stimulation of sebaceous glands, and male social behavior.1,2 SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/19 UR - accesspediatrics.mhmedical.com/content.aspx?aid=6736839 ER -