TY - CHAP M1 - Book, Section TI - Chapter 133. Hematopoietic Cell Transplantation A1 - Woolfrey, Ann E. A1 - Carpenter, Paul A. A1 - Sanders, Jean E. A2 - Rudolph, Colin D. A2 - Rudolph, Abraham M. A2 - Lister, George E. A2 - First, Lewis R. A2 - Gershon, Anne A. PY - 2011 T2 - Rudolph's Pediatrics, 22e AB - Hematopoietic cell transplantation (HCT) transfers a small number of hematopoietic stem cells (HSC) from a donor to a recipient, where they are able to differentiate and proliferate to restore a normal hematopoietic and immune system (see eFig. 133.1). HCT is performed in patients with life-threatening hematologic disorders or as a means to restore hematopoietic function following administration of otherwise lethal doses of chemotherapy or radiation for treatment of resistant malignancies. HCT also has the potential to cure disorders resulting from defects in the pluripotent progenitor cells or in a single hematopoietic lineage. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/29 UR - accesspediatrics.mhmedical.com/content.aspx?aid=6723823 ER -