TY - CHAP M1 - Book, Section TI - Chapter 275. Neisseria Meningitidis A1 - Estabrook, Michele A2 - Rudolph, Colin D. A2 - Rudolph, Abraham M. A2 - Lister, George E. A2 - First, Lewis R. A2 - Gershon, Anne A. PY - 2011 T2 - Rudolph's Pediatrics, 22e AB - Neisseriameningitidis is a common commensal bacterium of the human upper respiratory tract. Colonization infrequently leads to disseminated disease, but the resulting meningitis and sepsis can be fulminant and rapidly fatal in healthy children and adults. Among survivors, 11% to 19% are left with disabilities such as neurological deficit, hearing loss, or limb amputation.1,2 Despite advances in vaccine technology, N meningitidis remains a significant worldwide pathogen and the cause of epidemic meningitis. Children and young adults bear the burden of disease. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/18 UR - accesspediatrics.mhmedical.com/content.aspx?aid=7027199 ER -