TY - CHAP M1 - Book, Section TI - Chapter 285. Streptococcus Group A Infections A1 - Schleiss, Mark R. A1 - Kaplan, Edward L. A2 - Rudolph, Colin D. A2 - Rudolph, Abraham M. A2 - Lister, George E. A2 - First, Lewis R. A2 - Gershon, Anne A. PY - 2011 T2 - Rudolph's Pediatrics, 22e AB - Streptococcus pyogenes infections were likely responsible for the apparent scarlet fever epidemic described by Hippocrates in the 5th century BC. The history of S pyogenes has been the subject of a comprehensive review.1 The first modern description of streptococcal infection was the demonstration of the organism in patients with erysipelas and wound infection in 1874. The organism was designated Streptococcus pyogenes by Rosenbach in the late 19th century. In the early 1930s, Rebecca Lancefield’s classification of the β-hemolytic strains into characteristic distinct serogroups led to the recognition that serogroup A isolates (S pyogenes) were the streptococcal strains most commonly responsible for pharyngitis and impetigo/pyoderma. Streptococcus pyogenes is one of the most important infectious agents encountered in clinical practice causing infections of the upper respiratory tract and of the skin, that causes a variety of severe systemic infections, including toxic shock syndrome and life-threatening skin and soft tissue infections. Infection with this pathogen is also causally linked to two serious nonsuppurative complications, acute rheumatic fever and acute glomerulonephritis. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/29 UR - accesspediatrics.mhmedical.com/content.aspx?aid=7028185 ER -