TY  - CHAP
M1  - Book, Section
TI  - Chapter 301. Malassezia Furfur
A1  - Powell, Dwight A.
A2  - Rudolph, Colin D.
A2  - Rudolph, Abraham M.
A2  - Lister, George E.
A2  - First, Lewis R.
A2  - Gershon, Anne A.
PY  - 2011
T2  - Rudolph's Pediatrics, 22e
AB  - The  genus  Malassezia  includes  11  species  associated  with  significant  human  disease1(eTable  301.1).  The  organisms  are  dimorphic  with  both  yeast  and  mycelial  growth.  With  the  exception  of  M  pachydermatis,  all  other  Malassezia  species  require  lipid  supplementation  of  standard  fungal  growth  media  for  isolation.  When  Sabouraud  media  is  overlaid  with  sterile  olive  oil,  Malassezia  species  grow  within  5  to  14  days.2  Isolation  on  this  medium  causes  colonies  to  coalesce,  making  species  identification  difficult.  Although  species  identification  is  rarely  important  in  clinical  practice,  several  commercial  media  avoid  this  problem.  Dixon  medium  (containing  Tween  40  and  glycerol  monooleate)  and  Leeming  and  Notman  agar  (containing  Tween  60,  glycerol,  and  full-fat  cow  milk)  are  selective  media  for  Malassezia  isolation.  Rapid  identification  techniques,  such  as  identification  of  Malassezia  DNA  by  polymerase  chain  reaction,  have  been  utilized  in  study  settings.3  Malassezia  species  are  normal  residents  of  human  skin,  usually  found  in  sebum-rich  areas  such  as  the  trunk,  face,  and  scalp.  Extensive  studies  on  skin  colonization  have  shown  that  the  skin  of  healthy  newborn  infants  becomes  colonized  with  Malassezia  species  within  the  first  several  months  of  life.  Over  50%  of  prematurely  born  infants  requiring  prolonged  hospitalization  become  colonized  within  2  weeks  of  life.4,5  Ninety  to  100%  of  adolescents  and  adults  have  saprophytic  skin  colonization  with  Malassezia  species.6  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2024/04/20
UR  - accesspediatrics.mhmedical.com/content.aspx?aid=7029066
ER  -