TY - CHAP M1 - Book, Section TI - Chapter 311. Epstein-Barr Virus Mononucleosis A1 - Hunt, Garrett A1 - Brady, Michael T. A2 - Rudolph, Colin D. A2 - Rudolph, Abraham M. A2 - Lister, George E. A2 - First, Lewis R. A2 - Gershon, Anne A. PY - 2011 T2 - Rudolph's Pediatrics, 22e AB - The Epstein-Barr virus (EBV) is recognized as the major cause of heterophil-positive and heterophil-negative infectious mononucleosis. Manifestations of EBV infection are varied and range from asymptomatic infection to fulminant lymphoproliferative disease. The virus is associated with a number of malignancies, including African Burkitt lymphoma, nasopharyngeal carcinoma, Hodgkin disease, and a spectrum of posttransplant lymphoproliferative diseases. The specific role of EBV in each tumor is now defined, in a number of circumstances, to the level of specific cell type and receptors, intracellular pathways, gene expression, and cytokine production. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/28 UR - accesspediatrics.mhmedical.com/content.aspx?aid=7029999 ER -