TY  - CHAP
M1  - Book, Section
TI  - Chapter 391. Gastrointestinal Disorders Associated with Immunodeficiency
A1  - Noel, Richard J.
A2  - Rudolph, Colin D.
A2  - Rudolph, Abraham M.
A2  - Lister, George E.
A2  - First, Lewis R.
A2  - Gershon, Anne A.
PY  - 2011
T2  - Rudolph's Pediatrics, 22e
AB  - Children  with  primary  or  acquired  immunodeficiency  are  at  increased  risk  for  infectious  and  inflammatory  gastrointestinal  disorders.1  The  risk  and  severity  of  infection  depends  on  the  type  of  immunodeficiency.  Individuals  with  deficiencies  of  antibody  response  are  predisposed  to  extracellular  bacterial  infections  and  intestinal  pathogens.  Patients  with  deficiencies  of  T  cells  are  predisposed  to  both  intracellular  and  extracellular  infections.  In  addition,  patients  with  primary  immunodeficiencies  are  more  prone  to  develop  autoimmune  disorders  because  of  their  decreased  ability  to  distinguish  self-organisms  from  foreign  organisms.  Autoimmune  diseases  and  celiac  disease  are  more  common  in  the  IgA-deficient  patients.  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2024/04/20
UR  - accesspediatrics.mhmedical.com/content.aspx?aid=7036053
ER  -