TY  - CHAP
M1  - Book, Section
TI  - Chapter 488. Kawasaki Disease
A1  - Son, Mary Beth
A1  - Newburger, Jane W.
A2  - Rudolph, Colin D.
A2  - Rudolph, Abraham M.
A2  - Lister, George E.
A2  - First, Lewis R.
A2  - Gershon, Anne A.
PY  - 2011
T2  - Rudolph's Pediatrics, 22e
AB  - Kawasaki  disease  (KD),  an  acute  febrile  illness  of  childhood,  was  described  in  Japan  in  1967  by  Dr.  Tomasaku  Kawasaki  as  the  mucocutaneous  lymph  node  syndrome.1  A  vasculitis  of  medium-sized  vessels,  KD  has  a  predilection  for  the  coronary  arteries,  and  20%  to  25%  of  untreated  children  develop  coronary  artery  aneurysms.  Fortunately,  a  regimen  of  intravenous  immunoglobulin  and  aspirin  reduces  the  incidence  of  coronary  artery  abnormalities  to  less  than  5%.2  Nonetheless,  KD  is  a  leading  cause  of  acquired  heart  disease  in  children  in  North  America  and  Japan.  Furthermore,  the  etiology  of  KD  remains  elusive,  impeding  the  development  of  targeted  therapy  and  diagnostic  testing.  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2024/04/17
UR  - accesspediatrics.mhmedical.com/content.aspx?aid=7048488
ER  -