TY - CHAP M1 - Book, Section TI - Chapter 513. Bronchopulmonary Dysplasia A1 - Murphy, Timothy D. A2 - Rudolph, Colin D. A2 - Rudolph, Abraham M. A2 - Lister, George E. A2 - First, Lewis R. A2 - Gershon, Anne A. PY - 2011 T2 - Rudolph's Pediatrics, 22e AB - Bronchopulmonary dysplasia (BPD)—sometimes called chronic lung disease of infancy—is a disorder of lung injury and repair in infants who developed respiratory failure after birth and is characterized by persistent respiratory signs and symptoms. The pathogenesis of BPD is related to prematurity and the treatment of the accompanying early respiratory failure; the treatment interacts with the immature developing lung, causing further injury and delayed repair. The injurious effects of treatment include barotrauma from positive-pressure ventilation and oxygen toxicity. However, other therapies developed in the past 40 years have led to a different clinical, histological, and radiographic presentation and have redefined the condition. For a more detailed discussion of the pathogenesis, risk factors and prevention of BPD see Chapter 59. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/20 UR - accesspediatrics.mhmedical.com/content.aspx?aid=7051627 ER -