TY - CHAP M1 - Book, Section TI - Chapter 527. Hypothyroidism in the Infant A1 - Fisher, Delbert A. A2 - Rudolph, Colin D. A2 - Rudolph, Abraham M. A2 - Lister, George E. A2 - First, Lewis R. A2 - Gershon, Anne A. PY - 2011 T2 - Rudolph's Pediatrics, 22e AB - Causes of hypothyroidism are listed in Table 527-1. Transient neonatal hypothyroidism occurs in premature infants, and may be caused by drugs or maternal antibodies. The most common cause of nonendemic congenital hypothyroidism is defective thyroid embryogenesis. Inborn defects in thyroid hormone synthesis or action are the second most common cause of congenital hypothyroidism.1-13 Other causes include intrauterine exposure to goitrogenic agents and hypothalamic-pituitary disorders. These usually occur in the setting of panhypopituitarism, but isolated defects in thyrotropin-releasing hormone (TRH) or thyroid-stimulating hormone (TSH) do occur.5-7 SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/10/07 UR - accesspediatrics.mhmedical.com/content.aspx?aid=7053228 ER -