TY  - CHAP
M1  - Book, Section
TI  - Chapter 528. Acquired Hypothyroidism
A1  - Fisher, Delbert A.
A2  - Rudolph, Colin D.
A2  - Rudolph, Abraham M.
A2  - Lister, George E.
A2  - First, Lewis R.
A2  - Gershon, Anne A.
PY  - 2011
T2  - Rudolph's Pediatrics, 22e
AB  - Hypothyroidism  can  develop  at  any  age  among  previously  healthy  children,  although  it  is  more  common  among  girls.  Growth  retardation  is  an  early  sign.  Iodine  deficiency  remains  a  major  cause  of  hypothyroidism,  but  the  worldwide  incidence  is  decreasing.  A  high  proportion  of  patients  have  circulating  antithyroid  antibodies  characterizing  an  autoimmune  process  (Hashimoto  thyroiditis).  Among  others,  acquired  juvenile  hypothyroidism  can  be  caused  by  exposure  to  goitrogenic  agents,  thyroid  dysgenesis,  late  onset  of  hypothyroidism  caused  by  an  inborn  error  of  thyroidal  biosynthesis,  acquired  hypothalamic  or  pituitary  hypothyroidism,  or  endemic  factors.1-6  As  part  of  the  clinical  history,  the  physician  should  inquire  about  potential  intake,  or  contact  through  environmental  or  familial  occupational”  sources,  with  the  known  potential  goitrogens  listed  in  Table  527-2.  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2024/04/18
UR  - accesspediatrics.mhmedical.com/content.aspx?aid=7053333
ER  -