TY - CHAP M1 - Book, Section TI - Chapter 4. Bilirubin Metabolism and Transport A1 - Bellarosa, Cristina A1 - Muchova, Lucie A1 - Vitek, Libor A1 - Tiribelli, Claudio A2 - Stevenson, David K. A2 - Maisels, M. Jeffrey A2 - Watchko, Jon F. PY - 2012 T2 - Care of the Jaundiced Neonate AB - Unconjugated bilirubin (UCB), the principal mammalian bile pigment, is the end intravascular product of heme catabolism. Like many weakly polar, poorly soluble compounds, UCB is transported in blood tightly bound to albumin, with less than 0.01% of total bilirubin circulating in an unbound form (free bilirubin [Bf]). This fraction governs UCB tissue flux, and is responsible for its pathophysiological effects on cells and tissues. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/28 UR - accesspediatrics.mhmedical.com/content.aspx?aid=56321714 ER -