TY - CHAP M1 - Book, Section TI - Blood Component Therapy A1 - McCreight, Audra L. A1 - Wickiser, Jonathan E. A2 - Schafermeyer, Robert A2 - Tenenbein, Milton A2 - Macias, Charles G. A2 - Sharieff, Ghazala Q. A2 - Yamamoto, Loren G. PY - 2014 T2 - Strange and Schafermeyer's Pediatric Emergency Medicine, 4e AB - It is common to underestimate quantitative blood loss in the setting of trauma. Careful and frequent monitoring of vital signs and hematocrit is critical in the detection of severe hemorrhage.Massive transfusion protocols exist to supply O-negative blood and other essential blood products for the resuscitation of the hemodynamically unstable trauma patient.Mild-to-severe reactions can occur during the transfusion process including fever, chills, nausea, hypotension, or shock. Whether this is caused by blood type incompatibility, antibodies to donor cells, or blood product contamination, the transfusion must be stopped immediately and the symptoms of the reaction treated aggressively. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1105686069 ER -