TY - CHAP M1 - Book, Section TI - Patent Ductus Arteriosus A1 - Gomella, Tricia Lacy A1 - Cunningham, M. Douglas A1 - Eyal, Fabien G. A1 - Tuttle, Deborah J. PY - 2013 T2 - Neonatology: Management, Procedures, On-Call Problems, Diseases, and Drugs, 7e AB - The ductus arteriosus is a large vessel that connects the main pulmonary trunk (or proximal left pulmonary artery) with the descending aorta, some 5–10 mm distal to the origin of the left subclavian artery. In the fetus, it serves to shunt blood away from the lungs and is essential (closure in utero may lead to fetal demise or pulmonary hypertension). In full-term healthy newborns, functional closure of the ductus occurs rapidly after birth. Final functional closure occurs in almost half of full-term infants by 24 hours of age, in 90% by 48 hours, and in all by 96 hours after birth. Patent ductus arteriosus (PDA) refers to the failure of the closure process and continued patency of this fetal channel. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1107524754 ER -