TY - CHAP M1 - Book, Section TI - Seizure Activity A1 - Gomella, Tricia Lacy A1 - Cunningham, M. Douglas A1 - Eyal, Fabien G. A1 - Tuttle, Deborah J. PY - 2013 T2 - Neonatology: Management, Procedures, On-Call Problems, Diseases, and Drugs, 7e AB - The nurse reports that an infant is having abnormal movements of the extremities consistent with seizure activity. Seizures in the neonate are common and are more prevalent during the neonatal period than any other time. Neonatal seizures may be harmful to the immature brain and may have adverse long-term neurodevelopmental outcomes. Incidence is 2.5–3.5 per 1000 in full term, and up to 22% in preterm. Neonatal seizures are rarely idiopathic and are a common manifestation of a serious central nervous system disorder: hypoxic ischemic encephalopathy (∽30–50%; most common), intracranial hemorrhage (10–17%), metabolic abnormalities (hypocalcemia [6–15%]; hypoglycemia [6–10%]), central nervous system (CNS) infections (5–14%), infarction (7%), inborn errors of metabolism (3%), CNS malformations (5%), and unknown (10%). SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1107528036 ER -