TY - CHAP M1 - Book, Section TI - Intracranial Infections A1 - Wells, Robert G. PY - 2015 T2 - Diagnostic Imaging of Infants and Children AB - Congenital infections are acquired by the maternal hematogenous-transplacental route or by exposure to organisms during passage through the birth canal. Most fetal bacterial infections are due to the ascent of organisms from the cervix into the amniotic fluid. Congenital infections of the central nervous system (CNS), however, are usually transmitted transplacentally. The TORCH organisms cause most of these CNS infections: Toxoplasma, other (coxsackievirus, syphilis, varicella-zoster, human immunodeficiency virus, and parvovirus B19), rubella, cytomegalovirus, and herpes simplex virus type 2 (HSV). These organisms can cause chorioretinitis, microcephaly, and focal cerebral calcification. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1148948913 ER -