TY - CHAP M1 - Book, Section TI - Thymic Aplasia and T-Cell Disorder A1 - Lau, Yu-Lung A1 - Lee, Pamela A2 - Stevenson, David K. A2 - Cohen, Ronald S. A2 - Sunshine, Philip PY - 2015 T2 - Neonatology: Clinical Practice and Procedures AB - As detailed in chapter 49, host defense mechanisms against pathogens are defective in the newborn as a result of immature immunity. Preterm infants are particularly vulnerable to infections associated with prematurity-related complications and medical interventions. The recognition of inborn errors of immunity and differentiation from functional immaturity of the immune system pose a diagnostic challenge. An organized clinical approach is essential to facilitate early diagnosis, which has a significant impact on prognosis and survival. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1109795924 ER -