TY - CHAP M1 - Book, Section TI - Parvovirus B19 Infection A1 - Aziz, Natali A1 - Norton, Mary E. A2 - Stevenson, David K. A2 - Cohen, Ronald S. A2 - Sunshine, Philip PY - 2015 T2 - Neonatology: Clinical Practice and Procedures AB - Human parvovirus B19, a single-stranded DNA virus, is a member of the erythrovirus genus within the Parvoviridae family and the only erythrovirus that is a pathogen in humans.1 Human parvovirus was first identified by electron microscopy in 1975 and was associated with clinical disease approximately a decade later.2 It is the etiologic organism that manifests clinically as erythema infectiosum (fifth disease), a common childhood viral exanthem. In immunocompetent adults, infection with B19 is generally asymptomatic or mild. It is most commonly transmitted through respiratory droplets, and primary B19 infection in pregnant women can also result in vertical transmission to the fetus. Although most commonly asymptomatic for both mother and fetus, in some cases primary or acute infection in pregnancy may lead to adverse perinatal outcomes, including spontaneous abortion, hydrops fetalis, and fetal demise. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/08 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1109796506 ER -