TY - CHAP M1 - Book, Section TI - Treating Epilepsy in the Presence of Sleep Disorders A1 - Tinuper, Paolo A1 - Bisulli, Francesca A1 - Provini, Federica A1 - Geyer, James D. A1 - Carney, Paul R. A2 - Duchowny, Michael A2 - Cross, J. Helen A2 - Arzimanoglou, Alexis Y1 - 2017 N1 - T2 - Pediatric Epilepsy AB - Sleep disorders have an adverse impact on daily living for both children and their caregivers.1 Sleep disturbance and lack of restful sleep can masquerade as a myriad of clinical problems, including inattention, depression, headache, and seizures. While most neurological disorders are well characterized during the waking state, descriptions of pathophysiology, signs and comorbidities are frequently poorly described during sleep. Physiologic changes associated with sleep can cause an alteration of signs and function during both REM (rapid eye movement) and non-REM (NREM) sleep. These changes may include alterations in muscle tone, central control of autonomic functions, and changes in cortical neurotransmitter system interaction and balance. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1138411863 ER -