TY - CHAP M1 - Book, Section TI - Clinical Trials Versus Anecdotal Reports A1 - Nabulsi, Mona A1 - Mikati, Mohamad A. A2 - Duchowny, Michael A2 - Cross, J. Helen A2 - Arzimanoglou, Alexis Y1 - 2017 N1 - T2 - Pediatric Epilepsy AB - The choice of antiepileptic drugs (AEDs) entails a number of considerations detailed later. All these considerations cannot be fully or adequately addressed by controlled studies alone, and are thus grounds for individualization of therapy. Although evidence-based data from randomized controlled trials (RCTs) on drug efficacy are a critical part of the choice, as they provide an objective method to compare efficacy, they often do not address many other aspects that are important in such choices such as comparative efficacy, comorbidity, and ease of use. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1138412201 ER -