TY - CHAP M1 - Book, Section TI - Inborn Errors of Folate and Cobalamin Transport and Metabolism A1 - Watkins, David A1 - Morel, Chantal F. A1 - Rosenblatt, David S. A2 - Sarafoglou, Kyriakie A2 - Hoffmann, Georg F. A2 - Roth, Karl S. Y1 - 2017 N1 - T2 - Pediatric Endocrinology and Inborn Errors of Metabolism, 2e AB - The inborn errors of folate and cobalamin (Cbl) transport and metabolism, resulting from defects in a transport system or from enzymatic deficiency, lead to decreased availability of vitamin coenzymes required for cellular metabolism. Inherited disorders of folate metabolism include those characterized by abnormal absorption and transport and those caused by enzyme deficiencies, either primary or secondary, due to Cbl coenzyme defects (Figure 19-1). Inherited disorders of Cbl metabolism are also classified as those involving absorption and transport (Figure 19-2) and those involving intracellular utilization (Figure 19-3). SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1140317038 ER -