TY  - CHAP
M1  - Book, Section
TI  - Cushing Syndrome
A1  - Charmandari, Evangelia
A1  - Kyritsi, Eleni Magdalini
A1  - Sarafoglou, Kyriakie
A1  - Stratakis, Constantine A.
A1  - Chrousos, George P.
A2  - Sarafoglou, Kyriakie
A2  - Hoffmann, Georg F.
A2  - Roth, Karl S.
Y1  - 2017
N1  - 
T2  - Pediatric Endocrinology and Inborn Errors of Metabolism, 2e
AB  - Cushing  syndrome  (CS)  is  characterized  by  increased  circulating  glucocorticoid  concentrations.  It  is  very  rare  in  childhood  and  adolescence,  with  the  most  common  cause  of  CS  being  iatrogenic,  owing  to  chronic  or  excessive  administration  of  exogenous  glucocorticoids  in  the  form  of  topical,  inhaled,  or  oral  corticosteroids  for  the  treatment  of  many  non-endocrine  diseases,  including  pulmonary,  autoimmune,  dermatologic,  hematologic,  and  neoplastic  disorders.1,2  The  overall  incidence  of  CS  is  approximately  2  to  5  new  cases  per  million  people  per  year  and  only  10%  of  these  cases  occur  in  children.  There  is  a  female-to-male  predominance,  which  decreases  with  younger  age  and  may  even  lead  to  a  male-to-female  predominance  in  infants  and  young  toddlers.3,4  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/18
UR  - accesspediatrics.mhmedical.com/content.aspx?aid=1140319664
ER  -